"One of the hallmarks of solid tumors/cancers is a low oxygen cellular environment, scientifically called hypoxia. (Hypo = low, oxia = oxygen) Hypoxia typically causes cell death, such as in the case of a stroke or pulmonary embolism, but cancer cells have adapted to survive and thrive in these situations. Because of these concerns, oxygenation therapy can play a helpful role in overcoming a hypoxic cellular environment. One such therapy is Hyperbaric Oxygen Therapy (HBOT), which is the administration of 100% oxygen at higher than normal atmospheric pressure. HBOT treatments increase the amount of dissolved oxygen in the blood, therefore increasing oxygen delivery to the tumor environment and reducing hypoxia. These therapies are commonly used to treat traumatic brain injury patients and are continuing to gain popularity as an adjunctive cancer therapy.HBOT is very safe and complications are extremely rare. There are several chemotherapies that may be contraindicated or at least need to be used with caution when combined with HBOT due to increased toxicity, including doxorubicin, bleomycin, disulfiram, cisplatin, and mafenide acetate. Additionally, proceed with caution or do not do HBOT if you have COPD or other lung condition. Other oxygen promoting activities and therapies include deep breathing, exercise, and yoga."