"Treatment-resistant depression (TRD) is a type of major depressive disorder (MDD) that does not respond well to traditional forms of treatment, such as antidepressant medications and psychotherapy. People with TRD may experience severe symptoms that can interfere with their ability to function in day-to-day life.
Signs of Treatment-Resistant Depression
The signs and symptoms of TRD can vary from person to person and are comparable to the common symptoms of major depressive disorder (MDD). Distinguishing between the two will require a comprehensive evaluation by a mental health professional.
Common symptoms of TRD include:
Persistent sadness or feelings of emptiness
Angry outbursts, irritability, or frustration over small matters
Loss of interest or pleasure in activities you once enjoyed
Sleep disturbances, including insomnia or sleeping too much
Fatigue or decreased energy
Changes in appetite or weight
Anxiety, restlessness, or agitation
Slowed thinking, speaking, or body movements
Feelings of worthlessness or guilt
Difficulty concentrating, making decisions, or remembering things
Frequent thoughts of death or suicide
Ultimately, you will need the guidance of a specialist to make an accurate diagnosis but if you have been living with depression and not seeing the results you want from treatment, it"s important to consult with your doctor to see if you have Treatment-Resistant Depression."
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